Preservation of glucose in blood samples
OwnerEdward P. Marbachinventor
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Abstract
A process and preservatives for preventing glycolysis in blood samples so as to preserve the glucose content and lactic acid content thereof. The preservatives do not produce any significant hemolysis in the blood sample, and they do not interfere with any of the known blood constituents. The preservatives comprise salts of Iodoacetic acid, such as Tris-Iodoacetate [(CH.sub.2 OH).sub.3 NH.sub.3 CO.sub.2 -- CH.sub.2 I]; salts of Bromoacetic acid, such as Tris-Bromoacetate [(CH.sub.2 OH).sub.3 NH.sub.3 CO.sub.2 -- CH.sub.2 Br], or Sodium Bromoacetate [NaO.sub.2 CCH.sub.2 Br]; and salts of mono Chloroacetic acid (ClCH.sub.2 COOH), such as Sodium Chloroacetate (NaO.sub.2 CCH.sub.2 Cl).
Claims10
A preserved sample including whole blood and a preservative to preserve the glucose content of said whole blood, said preservative being selected from a group consisting of Tris-Iodoacetate, a salt of Bromoacetic acid or a salt of Chloroacetic acid.
A process for preventing glycolysis in a whole blood sample which comprises adding a preservative selected from a group consisting of Tris-Iodoacetate, a salt of Bromoacetic acid or a salt of Chloroacetic acid to the whole blood sample.
A process for preventing glycolysis in a whole blood sample which comprises adding a preservative selected from a group consisting of Tris-Bromoacetate Sodium Chloroacetate or Sodium Bromoacetate to the whole blood sample.
Dependencies are inferred from the claim text.