Bottle for sterile dispensing of flowable contents

The combination of a bottle closure device having an interior chamber and an internally threaded lower neck, dispensing means carried on and extending through an opening in the upper end of said closure device and in dispensing communication with said interior chamber, closure means mounted in sealed engagement to the upper end of said closure device and covering said dispensing means;

• a bottle containing flowable contents having a bottle top with complementary external threads along a portion of its length and received within the lower end of said closure device for the sterile storage and dispensing of said flowable contents and having a continuous unbroken integrally formed top wall on said bottle top effective to maintain sterile conditions in said bottle;
• cutting means mounted in the interior chamber of and carried by said closure device in axial proximity to said top wall such that the cutting means can be displaced into cutting engagement with said top wall by axial advance of said closure device in its threaded engagement on said bottle top;
• screen means carried within said interior chamber of said device to retain any chips produced by said cutting means from being dispensed through said dispensing means;
• and a pair of closely spaced annular beads with a fillet therebetween on said bottle top axially spaced from said external threads and received within said closure device and a cooperative annular bead on said neck of said closure device axially spaced form the internal threads thereon, said cooperative annular bead received within said fillet to provide restraining and microbiological sealing means, yieldably restraining said axial displacement of said device on said bottle top to prevent inadvertent rotation of and axial displacement of closure device and displacement of said cutting means toward said top wall, and microbiologically sealing said interior chamber to the environment.