Dichlorocyclopropylphenyl bisbiguanide compounds, processes and compositions
AssigneeSterling Drug Inc.
InventorsFrederic A. Eustis, III, William G. Gorman, Frederick C. Nachod
Life of this patent
Estimating the term…
Abstract
Dichlorocyclopropylphenyl bisbiguanides are prepared by cyanoguanidine-amine condensations. Antimicrobial compositions thereof and their method of use are disclosed.
Claims8
1,1'-A-bis(5-(p-(2,2-dichlorocyclopropyl)phenyl)biguanide) having the structural formula ##STR7## wherein A is alkylene of two to twelve carbon atoms having the valence bonds attached to different carbon atoms or an acid addition salt thereof.
A composition for reducing the number of microbes in liquids, on surfaces or on living tissues which consists essentially of an antimicrobially effective amount of 1,1'-A-bis(5-(p-2,2-dichlorocyclopropyl)phenyl)biguanide) or an acid addition salt thereof and a compatible vehicle wherein A is alkylene of two to twelve carbon atoms having the valence bonds attached to different carbon atoms.
The process for reducing the number of microbes in liquids, on surfaces or on living tissues which comprises applying thereto an antimicrobially effective amount of
- a. 1,1'-A-bis(5-(p-(2,2-dichlorocyclopropyl)phenyl)biguanide) or an acid addition salt thereof or
- b. a composition consisting essentially of 1,1'-A-bis(5-(p-(2,2-dichlorocyclopropyl)phenyl)biguanide) or an acid addition salt thereof and a compatible vehicle.
- wherein A is alkylene of two to twelve carbon atoms having the valence bonds attached to different carbon atoms.
Dependencies are inferred from the claim text.