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US 4,053,624 AGranted
Indole-2-carbaldehyde compounds and blood sugar reducing compositions
AssigneeBoehringer Mannheim GmbH
InventorsManfred Hubner, Ruth Heerdt, Felix Schmidt, Max Thiel
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Abstract
New indole-2-carbaldehyde compounds of the formula ##STR1## wherein R.sub.1 is lower alkyl R.sub.2 is hydrogen, halogen, or lower alkyl or alkoxy, With the proviso that when R.sub.2 is halogen or ethyl, R.sub.1 can also be hydrogen And the physiologically compatible derivatives thereof, are outstandingly effective in lowering excessive blood sugar in mammals.
Claims15
Indole-2-carbaldehyde compound of the formula:
- ##STR5## wherein R.sub.1 is lower alkyl of up to 5 carbon atoms and
- R.sub.2 is hydrogen, halogen or lower alkyl or alkoxy with the proviso that when R.sub.2 is ethyl, R.sub.1 may be hydrogen
- and the physiologically compatible aldehyde derivatives thereof.
Method of depressing blood sugar in the subject which method comprises administering to such subject an effective amount of indole-2-carbaldehyde compound of the formula:
- ##STR6## wherein R.sub.1 is lower alkyl or hydrogen and
- R.sub.2 is hydrogen, halogen or lower alkyl or alkoxy with the proviso that when R.sub.2 is other than halogen or ethyl, R.sub.1 is alkyl,
- and the physiologically compatible aldehyde derivatives thereof.
Dependencies are inferred from the claim text.