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US 4,053,621 AGranted
1-[2-(.beta.Naphthyloxy)ethyl]-3-methylpyrazolone-(5) and antithrombotic and antithrombolytic compositions and methods utilizing them
AssigneeBayer Aktiengesellschaft
InventorsEike Moller, Karl Meng, deceased, Harald Horstmann, Friedel Seuter, Egbert Wehinger
Life of this patent
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Abstract
1-[2-(.beta.-Naphthyloxy)ethyl]-3-methylpyrazolone-(5) and its salts are useful in the treatment and prophylaxis of thrombotic conditions. The compound is prepared through the reaction of 2-(.beta.-naphthyloxy)ethylhydrazine with either an acetoacetate or an ester of tetrolic acid, or through the condensation of 3-methylpyrazolinone-(5) with a derivative of 2-(.beta.-naphthyloxy)ethane, optionally with subsequent salt formation.
Claims16
1-[2-(.beta.-naphthyloxy)ethyl]-3-methylpyrazolone-(5) or a pharmaceutically acceptable nontoxic salt thereof.
Dependencies are inferred from the claim text.