Live Newcastle disease virus vaccines
AssigneeSmithKline Corporation
InventorsJacqueline Gits, Nathan Zygraich
Life of this patent
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Abstract
The improved live Newcastle disease virus vaccines of the invention contain a cold or cold and temperature-sensitive strain of Newcastle disease virus obtained by U.V. or nitrous acid mutation. The vaccines are administered to chickens in the form of an aerosol.
Claims5
An improved vaccine against Newcastle disease comprising a pharmaceutical diluent for aerosol adminisitration and an effective dose of an attenuated cold and temperature-sensitive strain obtained from a Newcastle disease virus strain by ultraviolet mutagenesis thereof, said strain showing a significantly higher growth at 26.degree. C than its parent strain and having a significantly inhibited growth at 41.degree. C.
Dependencies are inferred from the claim text.