Derivatives of 3,3-bis-(4-hydroxyphenyl)-2-indolinone and process for the preparation thereof
AssigneeDoctor Andreu S.A.
InventorsAlfonso Hosta Pujol, Salvador Brosa Rabassa
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Abstract
This invention relates to a group of compounds derived from 3,3-bis-(4-hydroxyphenyl)-2-indolinone having an effective laxative activity. The process for their preparation comprises reacting a substituted 3,3-bis-(4-hydroxyphenyl)-2-indolinone with a compound of the group comprising ethyl chloroformiate, chloracetyl chloride, acetyl chloride, acetyl anhydride, propionyl chloride, propionyl anhydride and chlorosulphonic acid (in pyridine).
Claims4
A compound selected from the group consisting of 3,3-bis-(4-sulphoxyphenyl)-7-methyl-2-indoline, and the alkali metal or alkaline earth metal salts thereof.
The disodium salt of 3,3-bis-(4-sulphoxyphenyl)-7-methyl-2-indolinone.
3,3-bis-(4-sulphoxy-phenyl)-7-methyl-2-indolinone.
3,3-bis-(4-oxicarboethoxyphenyl)-7-methyl-2-indolinone.
Dependencies are inferred from the claim text.