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US 4,052,506 AGranted
Pharmaceutical compositions and method of producing anti-Parkinsonism activity
AssigneeSmithKline Corporation
InventorsCarl Kaiser, Robert G. Pendleton, Paulette E. Setler
Life of this patent
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Abstract
Pharmaceutical compositions and method of producing anti-Parkinsonism activity by administering internally a nontoxic effective quantity of a benzazepine derivative to an animal.
Claims10
A method of producing anti-parkinsonism activity which comprises administering internally to an animal requiring said activity a nontoxic amount sufficient to produce said activity of a compound of the formula:
- ##STR3## in which:
- R is hydrogen, lower alkyl of from 1 to 4 carbon atoms, hydroxyethyl or lower alkenyl of from 3 to 5 carbon atoms;
- R.sub.1 is hydroxy, methoxy, ethoxy or alkanoyloxy;
- R.sub.2 is hydrogen, hydroxy, methoxy, ethoxy or alkanoyloxy;
- R.sub.3 is hydrogen, chloro, bromo, fluoro, methyl or trifluoromethyl;
- and
- said alkanoyl moieties have from 2 to 5 carbon atoms,
- provided that when R.sub.1 and R.sub.2 are both methoxy or ethoxy, R is hydrogen, or a pharmaceutically acceptable acid addition salt of said compound.
5 more elements
Dependencies are inferred from the claim text.