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US 4,052,504 AGranted
Assay for thyroxine binding globulin
AssigneeCorning Glass Works
InventorsWilliam Hertl, Gerald Odstrchel
Life of this patent
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Abstract
Method of determining the concentration of thyroxine binding globulin (TBG) in a fluid sample. The method comprises the steps of adding to the sample an excess amount of thyroxine (T.sub.4) and then analyzing the sample for T.sub.4 via immunoassay technique in the presence and absence of a blocking agent to establish a binding differential. The differential is then correlated with a standard curve which relates known TBG concentrations to binding differentials obtained in a similar manner.
Claims6
A method of determining the concentration of thyroxine binding globulin in a sample, the method comprising the steps of
- 1. adding to the sample an excess amount of thyroxine;
- 2. analyzing the sample for thyroxine via separate immunoassays, one immunoassay being in the presence of a blocking agent and the other immunoassay being in the absence of a blocking agent to thereby establish a binding differential;
- and
- 3. then correlating that differential with a standard curve which relates known thyroxine binding globulin concentrations with binding differentials.
1 more element
Dependencies are inferred from the claim text.