Disubstituted triphenylmethylimidazoles
AssigneeBayer Aktiengesellschaft
InventorsKarl Heinz Buchel, Erik Regel, Manfred Plempel
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AssigneeBayer Aktiengesellschaft
InventorsKarl Heinz Buchel, Erik Regel, Manfred Plempel
Estimating the term…
Imidazoles of the formula ##STR1## and pharmaceutically acceptable nontoxic salts thereof, wherein X is methyl or chloro, Y is methyl or chloro, or, when Z is methyl or chloro, Y is hydrogen, and Z is methyl or chloro, or, when Y is methyl or chloro, Z is hydrogen, Are useful as antimycotics for the treatment of mycotic infections in humans and animals. The imidazoles may be produced by reacting the corresponding triphenylmethylcarbinol with a brominating or chlorinating agent and thereafter reacting the resultant triphenylmethyl halide, either with or without isolation, with imidazole in the presence or absence of an acid-binding agent, or they may be prepared by reacting a triphenylmethyl halide with imidazole, either in the presence or absence of an acid-binding agent.
1-(2,6-Dichlorophenyl-diphenyl)-methyl-imidazole or a pharmaceutically acceptable non-toxic salt thereof.
1-(2,3-Dichlorophenyl-diphenyl)-methyl-imidazole or a pharmaceutically acceptable non-toxic salt thereof.
1-(2-Chlorophenyl-2'-chlorophenyl-phenyl)methyl-imidazole or a pharmaceutically acceptable non-toxic salt thereof.
Dependencies are inferred from the claim text.