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US 4,051,261 AGranted
1-(P-Alkanoylphenyl) alkanols and derivatives
AssigneeSandoz Ltd.
InventorsPaul L. Anderson, Jeffrey Nadelson
Life of this patent
Estimating the term…
Abstract
1-(p-alkanoylphenyl) alkanols, e.g., 1-(p-acetophenyl)-2,2-dimethylpropanol, are prepared from p-alkanoylphenyl Grignard reagents and alkyl and aryl aldehydes or acyl or aroyl halides and are useful as hypolipidemic and anti-diabetic agents.
Claims10
A compound of the formula ##STR13## where R.sub.1 is t-butyl or cycloalkyl having 3 to 6 carbon atoms, and
- R.sub.2 is lower alkyl having 1 to 4 carbon atoms or lower alkenyl having 3 to 5 carbon atoms, and
- R.sub.3 is hydrogen or halo having an aomic weight of about 19 to 80,
- provided that when R.sub.1 is cycloalkyl, R.sub.2 is lower alkyl.
A compound of the formula ##STR14## where R.sub.2 is lower alkyl having 1 to 4 carbon atoms or lower alkenyl having 3 to 5 carbon atoms, and
- R.sub.3 is hydrogen or halo having an atomic weight of about 19 to 80.
Dependencies are inferred from the claim text.