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US 4,051,247 AGranted
Method of using 7-hydroxy-benzo[ij]quinolizine-2-carboxylic acid derivatives
AssigneeRiker Laboratories, Inc.
InventorsDietrich Schuppan, John F. Gerster, Charles M. Leir
Life of this patent
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Abstract
Certain substituted 6,7-dihydro-7-hydroxy-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acids and salt and ester derivatives thereof are described. These compounds are useful antibacterial agents. SP This is a division of application Ser. No. 567,510, filed Apr. 14, 1975, now U.S. Pat. No. 3,985,753.
Claims2
A method for inhibiting the growth of microorganisms which comprises applying to said microorganisms an effective growth-inhibiting amount of a compound of the formula ##STR24## wherein R.sup.1 is hydrogen, methyl or ethyl;
- R.sup.2 is methyl, ethyl, halogen, hydroxy, nitro, amino, acetamido or formamido;
- n is zero, one or two, and when n is two, R.sup.2 may be methylenedioxy or ethylenedioxy bonded to adjacent carbon atoms;
- and when R.sup.2 is ethyl, methoxy, nitro, amino, acetamido or formamido, and n is two, each R.sup.2 must be different;
- or a lower alkyl ester or pharmaceutically acceptable salt derivative thereof.
1 more element
Dependencies are inferred from the claim text.