Method of treating diseases by daily administration of 6-chloro-11.beta.,17.alpha.,21-trihydroxypregna-1,4,6-triene-3,20-dione
AssigneeSyntex (U.S.A.) Inc.
InventorEugene J. Segre
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Abstract
This invention relates to a method of treating allergic, dermatologic and rheumatic diseases in mammals which comprises daily orally administering to said mammal in a single dose an effective amount of 6-chloro-11.beta.,17.alpha.,21-trihydroxypregna-1,4,6-triene-3,20-dione.
Claims5
The method of treating allergic, dermatologic and rheumatic diseases in mammals while, at the same time, lessening the deleterious side effects associated with the hypothalamic-pituitary-adrenal (HPA) axis function during corticosteroid administration, which comprises daily orally administering to said mammal in a single dose in the morning an effective amount of from about 2.5 mg. to about 20 mg. of the compound 6-chloro-11.beta.,17.alpha.,21-trihydroxypregna-1,4,6-triene-3,20-dione.
A therapeutic composition useful for treating allergic, dermatologic and rheumatic diseases in mammals while, at the same time, lessening the deleterious side effects associated with the hypothalamic-pituitary-adrenal (HPA) axis function during corticosteroid administration, adapted to provide a daily oral single morning dose of an effective amount of from about 2.5 mg. to about 20 mg. of the compound 6-chloro-11.beta.,17.alpha.,21-trihydroxypregna-1,4,6-triene-3,20-dione.
Dependencies are inferred from the claim text.