1-Benzoyl-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)-urea, a novel and useful intermediate for the preparation of animal growth promoting agents
AssigneeAmerican Cyanamid Company
InventorGoro Asato
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Abstract
This invention relates to 1-benzoyl (and 1-substituted benzoyl)-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)ureas, novel and useful intermediates for the preparation of 1,2,3,4-tetrahydro-4-oxo-1-naphthylurea and certain derivatives thereof. The above tetrahydro-4-oxo-1-naphthyl-urea and certain derivatives thereof are animal growth promoting agents. This invention further relates to methods of preparation of said 1-benzoyl (and 1-substituted benzoyl) 3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)ureas.
Claims6
A compound of the formula:
- ##STR12## wherein X is selected from the group consisting of hydrogen, methyl, methoxy, chloro and nitro;
- Y is selected from the group consisting of hydrogen, chloro and nitro;
- and the racemic mixture and the optical isomers thereof.
A process for the preparation of a compound, racemic mixture and optical isomers thereof, of the formula:
- ##STR13## which comprises hydrolyzing a compound of the formula:
- ##STR14## wherein X is selected from the group consisting of hydrogen, methyl, methoxy, chloro and nitro;
- Y is selected from the group of consisting of hydrogen, chloro and nitro;
- and the racemic mixture and the optical isomers thereof.
Dependencies are inferred from the claim text.