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US 4,050,989 AGranted
Process of preparing desacyl-pepsidine with bacillus pumilus
AssigneeEisai Co., Ltd.
InventorsNoriaki Kuwana, Yoshikazu Hasegawa, Yukio Nozu
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Abstract
Novel desacyl-pepsidine and process for the preparation thereof comprising contacting N-acyl-pentapeptide with a bacterium which belongs to Bacillus pumilus. The new compounds are useful as pepsin-inhibitor and as intermediates for the preparation of N-acyl-pentapeptide homologues.
Claims9
A process for the preparation of desacyl-pepsidine which comprises contacting an N-acyl-pentapeptide with a bacterium belonging to Bacillus pumilus.
The process as claimed in claim 2 wherein the reaction time ranges from about 3 to 60 hours.
Dependencies are inferred from the claim text.