Compositions using cycloalkano-quinolone derivatives and their method of use

An anti-bacterial composition comprising a pharmacologically acceptable carrier and, as an active anti-bacterial ingredient, a cycloalkano-quinolone compound having the formula:

• ##STR10## wherein one of R.sub.1 and R.sub.2 represents a member selected from the group consisting of hydrogen, halogen, nitro, amino and lower alkanoyl amino, and the other of R.sub.1 and R.sub.2 taken together with R.sub.3 forms an alkylene bridge containing 3 to 5 carbon atoms,
• X is hydrogen or lower alkyl of up to 6 carbon atoms, which may be substituted by a member of the group consisting of halogen, hydroxyl, lower alkanoyloxy, lower alkoxy, phenoxy, benzyloxy, mercapto, lower alkylmercapto, lower carbocyclic arylsulfonyloxy, and lower alkylsulfonyloxy, or X is unsubstituted lower alkenyl including alkadienyl, or lower alkynyl, and
• Y is a member selected from the group consisting of hydroxyl and lower alkoxy;
• and the non-toxic salts thereof.