Augmentation of blood levels of aspirin
AssigneeBristol-Myers Company
InventorsVal F. Cotty, Francis J. Sterbenz, Kenneth J. Melman
Life of this patent
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Abstract
The normal dosage of 10 grains (648 mg.) of aspirin, when combined with about 5 to 15, preferably about 10, grains of acetaminophen, yields increased blood levels of unhydrolyzed aspirin shortly and for extended periods after oral ingestion; a small addition of caffeine enables attainment of still higher blood levels of aspirin.
Claims13
As a composition of matter, a dose of a mixture containing about 10 grains of acetaminophen and about 10 grains of acetylsalicylic acid, said dose being in the form of a powder, solution, slurry or one or more tablets and being adapted for substantially concurrent release of both of said acetaminophen and said acetylsalicylic acid to the body.
As a composition of matter, a dose of a mixture containing about 5 grains of acetaminophen and about 10 grains of acetylsalicylic acid, said dose being in the form of a powder, solution, slurry or one or more tablets and being adapted for substantially concurrent release of both of said acetaminophen and said acetylsalicylic acid to the body.
A compressed tablet comprising a homogeneous mixture of about 5 grains of acetaminophen and 5 grains of acetylsalicylic acid, said tablet being adapted for substantially concurrent release of said acetaminophen and said acetylsalicylic acid to the body.
Dependencies are inferred from the claim text.