Amino glycoside antibiotics having antibacterial activity
AssigneeSchering Corporation
InventorsDavid J. Cooper, Jay Allan Waitz, Mae Counelis, Jay Weinstein
Life of this patent
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Abstract
In the fermentation production of gentamicin C a plurality of additional antibiotic compounds are obtained. Four of these compounds, gentamicin A, gentamicin B, gentamicin B.sub.1 and gentamicin X exhibit significant anti-protozoal and anthelmintic activity while gentamicin B and B.sub.1 have significant antibacterial properties with markedly reduced side effects.
Claims5
A method of treating a bacterial infection which comprises administering to an animal having said infection an antibacterially effective quantity of a member selected from the group consisting of gentamicin B, gentamicin B.sub.1, gentamicin X, a non-toxic pharmaceutically acceptable acid addition salt, and a mixture thereof.
A pharmaceutical composition comprising an antibacterially effective quantity of a member selected from the group consisting of gentamicin B, gentamicin B.sub.1, gentamicin X, a non-toxic pharmaceutically acceptable acid addition salt and a mixture thereof together with an inert pharmaceutical carrier.
Dependencies are inferred from the claim text.