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US 4,049,700 AGranted
Ibuprofen p-hydroxyphenylurea ester
AssigneeThe Upjohn Company
InventorAnthony A. Sinkula
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Abstract
Ibuprofen p-hydroxyphenylurea ester having the formula II: ##STR1## was prepared from the free acid, ibuprofen [.+-.2-(p-isobutylphenyl)propionic acid](I). The ester II above has the anti-inflammatory activity of the free acid, but in contradistinction to it, it has a pleasant taste, suitable for oral administration such as uncoated tablets, suspensions or syrups, for the treatment of inflammatory conditions, particularly arthritis.
Claims1
Ibuprofen p-hydroxyphenyurea ester having the formula II:
- ##STR3##
Dependencies are inferred from the claim text.