Heterocyclic esters of alkylphenyl benzopyrans
AssigneeAbbott Laboratories
InventorMartin Winn
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AssigneeAbbott Laboratories
InventorMartin Winn
Estimating the term…
Heterocyclic esters of benzopyrans represented by the formula ##STR1## wherein n is 1 or 2; each R and R.sub.1 are the same or different members of the group consisting of hydrogen or loweralkyl; R.sub.2 is loweralkyl; R.sub.3 is ##STR2## WITH Y' being a straight or branched chain alkylene group having from one to eight carbon atoms, a is an integer from 1 to 4, b is an integer from 1 to 4, X is CH.sub.2, O, S or NR.sub.7 with R.sub.7 being hydrogen or loweralkyl, with the limitation that when X is O, S, or NR.sub.7, a and b each must be 2; R.sub.8 is hydrogen or loweralkyl; Y is a straight or branched chain alkylene group having from one to ten carbon atoms; and each R.sub.4 and R.sub.5 and R.sub.6 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl; and the pharmaceutically acceptable salts thereof.
A compound of the formula ##STR8## wherein n is 1 or 2;
1-[4(morpholino)butyryloxy]-8-(4-phenyl-1-me thylbutyl)-6,6,9-trimethyl-7,8,9,10-tetrahydro-6H-dibenzo[b,d]-pyran hydrochloride.
1-[4-morphol ino)butyryloxy]-8-(4-p-fluorophenyl-1-methybutyl)-6,6,9-trimethyl-7,8,9,10- tetrahydro-6H-dibenzo[b,d]pyran hydrobromide.
4,4-dimethyl-7-(4-p-fluorophenyl-1-methylb utyl)-9-[4-(morpholino)-butyryloxy]-1,2,3,4-tetrahydrocyclopenta[c][1]benzo pyran hydrochloride.
4,4-dimethyl-9-[4 -(morpholino)butyryloxy]-7-(4-phenyl-1-methylbutyl)-1,2,3,4-tetrahydrocyclo penta[c][1]benzopyran hydrochloride.
Dependencies are inferred from the claim text.