Alkoxy and alkylthioalkylureido cephalosporins

A compound of the formula ##STR214## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, diphenyl-lower alkyl, tri(lower alkyl)silyl, trihaloethyl, an alkali metal ion, an alkaline earth metal ion, dibenzylamine, N,N-dibenzylethylenediamine, methylamine, triethylamine, N-ethylpiperidine, or ##STR215## R.sub.1 is in the .alpha.-configuration and is hydrogen or methoxy;

• R.sub.2 is lower alkyl;
• Y is O or S;
• R.sub.3 is hydrogen or lower alkyl;
• A is straight or branched chain alkylene of 1 to 6 carbons;
• R.sub.4 is phenyl, phenyl-lower alkyl, substituted phenyl or phenyl-lower alkyl wherein said phenyl substituent is one or two members selected from the group consisting of halogen, lower alkyl of 1 to 4 carbons, lower alkoxy of 1 to 4 carbons, and hydroxy, or a substituted or unsubstituted heterocyclic selected from the group consisting of 2-thienyl, 3-thienyl, 2-furyl, and 3-furyl wherein said heterocyclic substituent is attached at an available carbon atom and is halogen or lower alkyl of 1 to 4 carbons;
• R.sub.5 is hydrogen or lower alkyl;
• R.sub.6 is lower alkyl;
• and X is a heterothio selected from the group consisting of ##STR216## and ##STR217## wherein R.sub.7 is hydrogen or lower alkyl of 1 to 4 carbons and R.sub.8 is hydrogen, lower alkyl of 1 to 4 carbons, methoxy, hydroxy, or halogen.