Physiologically active substances and fermentative process for producing the same
AssigneeSankyo Company, Limited
InventorsAkira Endo, Masao Kuroda, Akira Terahara, Yoshio Tsujita, Chihiro Tamura
Life of this patent
Estimating the term…
Abstract
Physiologically active substances ML-236 of the formula ##STR1## wherein R is hydrogen atom, hydroxy group or 2-methyl-butyryloxy group having cholesterol- and lipid-lowering effects in blood and liver and thus utility as hypocholesteremic and hypolipemic medicaments. They are obtained by cultivation of an ML-236-producing micro-organism belonging to the genus Penicillium in a culture medium and subsequent recovery thereof from a cultured broth.
Claims5
A process for the production of substances, ML-236A, ML-236B and ML-236C having the formulae, respectively, ##STR4## which comprises cultivating an ML-236-producing microorganism belonging to the genus Penicillium in a culture medium under aerobic condition and recovering said ML-236 substances from the cultured broth.
Dependencies are inferred from the claim text.