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US 4,048,430 AGranted
Mercaptopseudotrisaccharides
AssigneeSmithKline Corporation
InventorsDavid J. Cooper, John R. E. Hoover, Jerry A. Weisbach
Life of this patent
Estimating the term…
Abstract
Novel pseudodisaccharide compounds which are related to neamine are prepared. These compounds have a mercapto group or a derivative thereof at position 3 or 4 of the glucose moiety of neamine. The compounds have antibacterial activity and have utility as intermediates to pseudotrisaccharides.
Claims12
A compound of the formula ##STR5## where X and X' are each SR" or OR' but are not the same;
- each R is hydrogen or an amino protecting group;
- each R' is hydrogen or a hydroxy protecting group;
- R" is hydrogen or a mercapto protecting group;
- and
- Y is 3-amino-3-deoxy-D-glucopyranosyl, 3-acetamido-3-deoxy-D-glucopyranosyl, 3-acetamido-3-deoxy-2,4,6-O-triacety l-D-glucopyranosyl, or 3-acetamido-3-deoxy-2,4,6-O-tribenzyl-D-glucopyranosyl.
2 more elements
Dependencies are inferred from the claim text.