Phenylalkanoic acids
AssigneeThe Boots Company PLC
InventorsStewart S. Adams, Bernard J. Armitage, John S. Nicholson
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Abstract
Therapeutic compositions comprising 2-(hydroxy-substituted-4-biphenylyl)propionic acids and methods of treatment of inflammation, pain, fever and preventing blood platelet aggregation with these compounds.
Claims23
A therapeutic composition useful in the treatment of pain, inflammation or pyretic conditions or in preventing or inhibiting aggregation of blood platelets which comprises, as active ingredients, a compound of formula I ##STR13## wherein R.sub.22 and R.sub.23 are selected from hydrogen and halogen and Y is COOH,
- or a pharmaceutically acceptable ester or a salt of a compound wherein Y is COOH and a pharmaceutically acceptable carrier.
A method of treating inflammation in a patient requiring treatment therefor which comprises administering to said patient an effective amount of a compound of formula I ##STR14## wherein R.sub.22 and R.sub.23 are selected from hydrogen and halogen and Y is COOH,
- or a pharmaceutically acceptable ester or a salt of a compound wherein Y is COOH.
A method of treating pain in a patient requiring treatment therefor which comprises administering to said patient an effective amount of a compound of formula I ##STR15## wherein R.sub.22 and R.sub.23 are selected from hydrogen and halogen and Y is COOH, or a pharmaceutically acceptable ester or a salt of a compound wherein Y is COOH.
A method of treating pyretic conditions in a patient requiring treatment therefor which comprises adminstering to said patient an effective amount of a compound of formula I ##STR16## wherein R.sub.22 and R.sub.23 are selected from hydrogen and halogen and Y is COOH, or a pharmaceutically acceptable ester or a salt of a compound wherein Y is COOH.
A method of preventing or inhibiting aggregation of blood platelets in a patient requiring treatment therefor which comprises administering to said patient an effective amount of a compound of formual I ##STR17## wherein R.sub.22 and R.sub.23 are selected from hydrogen and halogen and Y is COOH, or a pharmaceutically acceptable ester or a salt of a compound wherein Y is COOH.
Dependencies are inferred from the claim text.