Radiopharmaceutical scanning agents
AssigneeMallinckrodt Inc.
InventorRobert George Wolfangel
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Abstract
Dispersions useful in preparing radiopharmaceutical scanning agents.
Claims20
A dispersion useful in forming an injectable radiopharmaceutical scanning agent comprising a stannous sulfur colloid dispersed in an aqueous buffer solution.
A dispersion useful in forming an injectable radiopharmaceutical scanning agent prepared by the method comprising
- a. forming a dispersion containing a sulfur colloid by reacting in an aqueous medium a thiosulfate with a pharmaceutically acceptable acid,
- b. interacting a pharmaceutically acceptable stannous salt with the dispersion of (a) and thereafter buffering the resulting dispersion.
method for preparing a dispersion of a stannous sulfur colloid in an aqueous buffer solution which is useful in forming an injectable radiopharmaceutical scanning agent comprising
- a. forming a dispersion containing a sulfur colloid by reacting in an aqueous medium a thiosulfate with a pharmaceutically acceptable acid,
- b. interacting a pharmaceutically acceptable stannous salt with the dispersion of (a) to form a dispersion containing a stannous sulfur colloid and buffering said dispersion contaning said stannous sulfur colloid.
An injectable radiopharmaceutical scanning agent comprising a technetium-99m labelled sulfur colloid to which stannous ions are attached dispersed in an aqueous buffer solution.
Dependencies are inferred from the claim text.