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US 4,048,230 AGranted
Aminoacetyl-acenaphthenes
AssigneeRichardson-Merrell Inc.
InventorsArthur D. Sill, Francis W. Sweet
Life of this patent
Estimating the term…
Abstract
Novel 3,6-bis basic ketone derivatives of acenaphthene, their preparation and use for the prevention and inhibition of viral infections are disclosed.
Claims5
A 3,6-bis-basic ketone of acenaphthene having the formula:
- ##STR18## wherein A is a straight or branched alkylene chain having from 1 to 6 carbon atoms;
- and Y is selected from the group consisting of:
- a. ##STR19## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, lower alkyl having from 1 to 6 carbon atoms, cycloalkyl having from 3 to 6 carbon atoms, alkenyl having from 3 to 6 carbon atoms in which the unsaturation is in a position other than the 1-position of the alkenyl group;
- b. ##STR20## wherein n is an integer of from 4 to 6, and R.sub.3 is selected from the group consisting of hydrogen, lower alkyl having from 1 to 4 carbon atoms, phenyl and benzyl in which said R.sub.3 group is linked to any of the heterocyclic carbon atoms;
- c. ##STR21## wherein X is selected from the group consisting of oxygen and NR.sub.4, in which R.sub.4 represents hydrogen or a lower alkyl group having from 1 to 4 carbon atoms;
- and the pharmaceutically acceptable salts thereof.
3 more elements
The compound 3,6-bis[2-(diethylamino)acetyl] acenaphthene and the pharmaceutically acceptable acid addition salts thereof.
The compound 3,6-bis[2-(dimethylamino)acetyl] acenaphthene the pharmaceutically acceptable acid addition salts thereof.
Dependencies are inferred from the claim text.