Certain 8-(2-tetrahydrofuryl)octanoic acid compounds with prostaglandin like biological effects
AssigneeAktieselskabet Grindstedvaerket
InventorsPoul Nedenskov, Karol Alster
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Abstract
This invention relates to therapeutically active 2,5-tetrahydrofurane derivatives, wherein the substituent in the 2-position is a group ROOC--(CH.sub.2).sub.7, in which R is hydrogen or lower alkyl, the 5-substituent being an alkyl or alkenyl group of 8 to 12 carbon atoms, which may be substituted with an oxygen atom, a hydroxy group or a lower alkyl group at the third carbon atom, counted from the furane ring, and to the production thereof.
Claims8
A tetrahydrofuran derivative of the formula ##STR4## wherein R.sup.1 represents hydrogen or a lower alkyl group, each of R.sup.2 and R.sup.3 represents hydrogen, or R.sup.2 and R.sup.3 together represents a further bond between the two carbon atoms, one of R.sup.4 and R.sup.5 represents hydrogen or a lower alkyl group and the other a hydroxy group, or R.sup.4 and R.sup.5 together represents an oxygen atom.
Dependencies are inferred from the claim text.