Back to results
US 4,046,905 AGranted
Anti-inflammatory, analgesic and antipyretic phenylacetic acids
AssigneeMerck & Co., Inc.
InventorsTsung-Ying Shen, Jorge P. Li, Conrad P. Dorn, Jr.
Life of this patent
Estimating the term…
Abstract
The invention relates to a novel class of 4-(benzoxazol-2-yl)phenylacetic acids, alcohols, esters, amides and the non-toxic pharmaceutically acceptable salts thereof and processes for their preparation. The invention further pertains to a class of (benzoxazol-2-yl)phenylacetic acids useful as antiinflammatory agents.
Claims10
A method of treating pain, fever and inflammation which comprises the administration to humans and animals of an analgesic, antipyretic or anti-inflammatory effective amount of a compound having the formula:
- ##STR8## or a pharmaceutically acceptable salt thereof, wherein R.sub..alpha. is hydrogen or methyl;
- R.sub.2, r.sub.3, x and Y are each hydrogen,
- chloro,
- bromo, or
- fluoro;
- and
- R.sub.4 is COOH;
- Coor, where R may be
- C.sub.1-5 alkyl,
- Conh.sub.2 ;
- ##STR9## where Y may be C.sub.1-3 alkyl.
8 more elements
Dependencies are inferred from the claim text.