Phenylpiperidines
AssigneeRoussel Uclaf
InventorsLucien Nedelec, Jacques Guillaume, Claude Dumont
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Abstract
Novel compounds selected from the group consisting of phenylpiperidines of the formula ##STR1## wherein X is selected from the group consisting of hydrogen and an acyl of aliphatic carboxylic acid of 2 to 6 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts possessing dopaminergic properties and some of which possess hypotensive properties and their preparation.
Claims11
A compound selected from the group consisting of phenylpiperidines of the formula ##STR15## wherein X is selected from the group consisting of hydrogen and an acyl of alkanoic acid of 2 to 6 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts.
A compound selected from the group consisting of N-benzyl-3-(3',4'-dimethoxyphenyl)-piperidine, a compound of the formula ##STR16## and a compound of the formula ##STR17## wherein Y is selected from the group consisting of --CH.sub.3 and benzyl and the dotted line is a double bond in the 2,3 or 3,4 position of piperidine.
A method of reducing hypertension in warm-blooded animals comprising administering to warm-blooded animals an hypotensively effective amount of 3-(3',4'-dihydroxyphenyl)-piperidine or its non-toxic, pharmaceutically acceptable acid addition salts.
Dependencies are inferred from the claim text.