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US 4,046,870 AGranted
Assay for free thyroid hormones
AssigneeCorning Glass Works
InventorsWilliam Hertl, Gerald Odstrchel
Life of this patent
Estimating the term…
Abstract
Method for determining the concentration of free (unbound) thyroid hormones (T.sub.3 or T.sub.4) in a fluid sample. The method comprises the steps of performing an immunoassay for total T.sub.3 or total T.sub.4 in the presence and absence of a blocking agent to establish a binding differential and then correlating that differential with a standard curve which relates known free thyroid hormone concentrations with binding differentials.
Claims7
A method for determining the concentration of free thyroid hormone in a fluid sample, the method comprising the steps of
- (1) performing separate immunoassays for thyroid hormone, one immunoassay being in the presence of a blocking agent and the other immunoassay being in the absence of a blocking agent to thereby establish a binding differential;
- and
- (2) then correlating that differential with a standard curve which relates known free thyroid hormone concentrations with binding differentials.
Dependencies are inferred from the claim text.