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US 4,046,787 AGranted
Novel 15-substituted prostanoic acids and esters
AssigneeAmerican Cyanamid Company
InventorsRobert Eugene Schaub, Martin Joseph Weiss
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Abstract
This disclosure describes compounds of the class of 15-substituted-9-keto(or 9-hydroxy)prostanoic acids and the esters and cationic salts thereof, useful as inhibitors of gastric acid secretion.
Claims16
A compound of the formula:
- ##STR9## wherein m is an integer from 5 to 8, inclusive;
- R.sub.1 is an alkyl group having from 3 to 6 carbon atoms, inclusive;
- R.sub.2 is selected from the group consisting of hydrogen and an alkyl group having up to 4 carbon atoms;
- X is selected from the group consisting of mercapto and lower alkanoylthio;
- and Y is a divalent radical selected from the group consisting of those of the formulae:
- ##STR10## and the pharmaceutically acceptable cationic salts thereof when R.sub.2 is hydrogen.
3 more elements
Dependencies are inferred from the claim text.