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US 4,046,774 AGranted
Process for N-phosphorylation of heterocyclic amines
AssigneeMobil Oil Corporation
InventorRoger P. Napier
Life of this patent
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Abstract
A process for N-phosphorylating heterocyclic amines, e.g., pyrrole, comprising treating the amine with a complex formed by a mixture of bromotrichloromethane and a trialkyl phosphite.
Claims5
A process for the N-phosphorylation of heterocyclic acidic amines having the following general formula:
- ##STR3## where R.sub.1 through R.sub.4 are selected from the group consisting of H, C.sub.1 -C.sub.25 alkyl, phenyl, carbalkoxyl, carboxy, nitro, alkythio, alkoxy, halo, and haloalkyl;
- and where R.sub.1 and R.sub.2 may be connected so as to form an aromatic ring;
- and where R.sub.1 and R.sub.2 and R.sub.3 and R.sub.4 may be connected to form respective aromatic rings comprising treating said amine with a complex formed by a mixture of bromotrichloromethane and a trialkyl phosphite having from 1-3 carbon atoms per alkyl group.
Dependencies are inferred from the claim text.