Crosslinked, porous, polyacrylate beads
AssigneeCalifornia Institute of Technology
InventorsAlan Rembaum, Shiao-Ping S. Yen, William J. Dreyer
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Abstract
Uniformly-shaped, porous, round beads are prepared by the co-polymerization of an acrylic monomer and a cross-linking agent in the presence of 0.05 to 5% by weight of an aqueous soluble polymer such as polyethylene oxide. Cross-linking proceeds at high temperature above about 50.degree. C or at a lower temperature with irradiation. Beads of even shape and even size distribution of less than 2 micron diameter are formed. The beads will find use as adsorbents in chromatography and as markers for studies of cell surface receptors.
Claims4
A composition consisting essentially of uniformly shaped, hydrophilic, swellable, porous, round beads, at least 80% having a diameter less than 2 microns and being the cross-linked polymer of acrylamide and 0.1 to 30 weight percent of a liquid diene or triene cross-linking agent.
Dependencies are inferred from the claim text.