Skin protective compositions
AssigneeCincinnati Milacron Inc.
InventorsRalph Kelly, Edmond Jean Ritter
Life of this patent
Estimating the term…
Abstract
Compositions effective for protecting the skin from dermatologic irritation are formed by incorporating a protective agent which is an organic compound containing two or more polar groups, e.g. carboxyl group, which are separated by at least 15 atoms the majority of which are carbon atoms and preferably containing a cyclic moiety of at least 5 atoms, e.g. the dimer of linoleic acid, in a pharmaceutically acceptable base.
Claims17
A skin protective lotion or creme consisting essentially of a skin irritation reducing effective amount of a protective agent and a non-aqueous emollient, humectant or surfactant;
- said lotion or creme capable of reducing skin irritation compared to said lotion or creme without protective agent when applied to the skin prior to contact with a skin irritant;
- said protective agent being dispersible in said lotion or creme;
- said protective agent containing two polar groups which are separated by a chain of at least 15 atoms a majority of which are carbon;
- said protective agent selected from the group consisting of:
- 1. esters and polyesters of the polymerized fatty acid product obtained from the polymerization of 2 to 4 molecules of a monomeric ethylenically unsaturated C.sub.12 to C.sub.26 fatty acid, said product containing 2 to 4 carboxyl groups;
- and an alcohol which is
- a. polyoxyalkylene ether containing 2 to 30 oxyalkylene units in which the alkylene radical contains 2 to 4 carbon atoms;
- b. a condensation product of alkylene oxide having 2 to 4 carbon atoms and polyamine having 2 to 4 amino groups and containing 2 to 8 carbon atoms in an aliphatic, cycloaliphatic or aromatic group;
- or
- c. a condensation product of ethylene oxide with a hydrophobic base formed by the condensation of propylene oxide with propylene glycol, having the general formula:
- ##STR35## wherein a is 1 to 150 b is 15 to 70 and
- c is 1 to 150;
- and
- 2.
A skin protective lotion or creme consisting essentially of a skin irritation reducing effective amount of a protective agent and a non-aqueous emollient, humectant or surfactant;
- said lotion or creme capable of reducing skin irritation compared to said lotion or creme without protective agent when applied to the skin prior to contact with a skin irritant;
- said protective agent being dispersible in said lotion or creme;
- said protective agent containing two polar groups which are separated by a chain of at least 15 atoms a majority of which are carbon;
- said protective agent selected from the group consisting of:
- 2. esters and polyesters of the polymerized fatty acid product obtained from the polymerization of 2 to 4 molecules of a monomeric ethylenically unsaturated C.sub.12 to C.sub.26 fatty acid, said product containing 2 to 4 carboxyl groups;
- and a polyol which is
- a. a polyoxyalkylene ether containing 2 to 30 oxyalkylene units in which the alkylene radical contains 2 to 4 carbon atoms;
- b. a condensation product of alkylene oxide having 2 to 4 carbon atoms and polyamine having 2 to 4 amino groups and containing 2 to 8 carbon atoms in an aliphatic, cycloaliphatic or aromatic group;
- or
- c. a condensation product of ethylene oxide with a hydrophobic base formed by the condensation of propylene oxide with propylene glycol, having the general formula:
- ##STR38## wherein a is 1 to 150
- b is 15 to 70 and
- c is 1 to 150.
Dependencies are inferred from the claim text.