11-(4-Piperidyl)dibenzo-diazepines
AssigneeAmerican Cyanamid Company
InventorsRobert Allis Hardy, Jr., Nicanor Quinones Quinones
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Abstract
The compounds, 11-(4-piperidyl)-5H-dibenzo[b,e] [1,4]diazepines, intermediates and methods of preparation thereof are described. They are useful as neuroleptic agents.
Claims20
A compound of the formula:
- ##STR8## wherein R.sub.1 is selected from the group consisting of hydrogen, C.sub.1 -C.sub.3 alkyl, and hydroxy C.sub.1 -C.sub.3 alkyl;
- R.sub.2 is selected from the group consisting of hydrogen and C.sub.1 -C.sub.3 alkyl;
- R.sub.3 and R.sub.4 are selected from the group consisting of hydrogen, C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy, halogen, hydroxy and trifluoromethyl;
- and nontoxic acid addition salts thereof.
The compound according to claim 1, 8-Chloro-5-methyl-11-(1-methyl-4-piperidyl)-5H-dibenzo[b,e][1,4]diazepine.
The compound according to claim 1, 5-Methyl-11-(1-methyl-4-piperidyl)-5H-dibenzo[b,e][1,4]diazepine.
The compound according to claim 1, 8-Methoxy-5-methyl-11-(1-methyl-4-piperidyl)-5H-dibenzo[b,e][1,4]diazepine .
The compound according to claim 1, 8-Chloro-11-(1-methyl-4-piperidyl)-5H-dibenzo[b,e][1,4]diazepine.
The compound according to claim 1, 8-Methyl-11-(1-methyl-4-piperidyl)-5H-dibenzo[b,e][1,4]diazepine.
Dependencies are inferred from the claim text.