Production of attenuated viruses
AssigneeBayer Aktiengesellschaft
InventorOtto-Christian Straub
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Abstract
There is disclosed novel non-antigenic attenuated viruses which non-specifically stimulate the natural defense mechanism of a host organism with a detectable non-specific induction of interferon; to methods for their production and to their use for the prophylaxis and treatment of viral and bacterial infections in human and veterinary medicine. The aforesaid term "non-antigenic attenuated virus" in this application means "an attenuated virus being incapable to cause an immunological cross-reaction with the original virus".
Claims3
A pharmaceutical composition containing as an active ingredient attenuated IPV virus which causes no immunological cross-reaction with unattenuated IPV virus and which stimulates the natural defense mechanism of cattle with a detectable non-specific induction of interferon and which is suitable for the prophylaxis and treatment of respiratory and genital tract infections in cattle, in admixture with a pharmaceutically acceptable diluent, wherein said active ingredient is contained in an amount equivalent to 10.sup.4 to 10.sup.8 CiD.sub.50 units/ml of virus.
Dependencies are inferred from the claim text.