Composition and method for determining the size and location of myocardial infarcts
AssigneeMassachusetts General Hospital
InventorEdgar Haber
Life of this patent
Estimating the term…
Abstract
Radioactive labelled antibody for cardiac myosin is injected intravenously after cardiac occlusion and is specifically absorbed in infarcted myocardium, as are radioactive labelled lower molecular weight fragments of the antibody such as (Fab').sub.2, (Fab'), and (Fv). The location and size of the myocardial infarct can be determined by measuring the intensity and location of radioactive emission externally of the heart.
Claims6
A composition comprising a physiologically acceptable injection vehicle and a member of the group consisting of radioactive labelled antibody for cardiac myosin and radioactive labelled lower molecular weight fragments of said antibody.
Dependencies are inferred from the claim text.