Aqueous solution suitable for dissipating available iodine contained in an iodophor
AssigneeFlow Pharmaceuticals, Inc.
InventorJoseph Zenon Krezanoski
Life of this patent
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Abstract
An aqueous solution suitable for dissipating, at a controlled rate, available iodine contained in an iodophor is disclosed. The aqueous dissipating solution contains sorbic acid or soluble salts thereof and ethylenediaminetetraacetic acid or soluble salts thereof. Preferably, the dissipating solution also contains an ammonium, alkali metal, or alkaline earth metal salt of a boron oxyacid. Also disclosed are techniques for sterilizing contact lenses and sterile solutions, suitable for maintaining sterility of a previously sterilized object, comprising admixtures of the dissipating solutions with iodophor solutions.
Claims19
A sterile aqueous solution suitable for dissipating available iodine contained in an iodophor at a controlled rate, consisting essentially of:
- a. from about 0.01% to about 5% by weight sorbic acid or a soluble salt thereof;
- and
- b. from about 0.01% to about 5% by weight ethylenediaminetetraacetic acid or a soluble salt thereof.
A sterile aqueous solution comprising an admixture of
- a. from about 1% to about 10% by weight of an aqueous iodophor solution comprising from about 0.00005% to about 10% by weight iodine, from about 0.0001% to about 20% by weight of a water soluble iodide salt or hydriotic acid, and from about 0.001% to about 25% by weight polyvinyl alcohol;
- and
- b. from about 90% to about 99% by weight of a sterile aqueous solution comprising from about 0.01% to about 5% by weight sorbic acid or a soluble salt thereof;
- from about 0.01% to about 5% by weight ethylenediaminetetraacetic acid or a soluble salt thereof;
- and about 0.1% to about 2% of an ammonium, alkali metal, or alkaline earth metal salt of a boron oxyacid.
A method of sterilizing contact lenses comprising:
- a. contacting said lens with an aqueous antiseptic iodophor solution comprising from about 0.00005% to about 10% by weight iodine, from about 0.0001% to about 20% by weight of a water soluble iodide salt or hydriotic acid, and from about 0.001% to about 25% by weight polyvinyl alcohol;
- and
- b. dissipating available iodine contained in said iodophor by adding to said aqueous iodophor solution in an amount of from about 90% to about 99% by weight based on the total weight of the combined solutions, an antioxidant having a redox potential adequate to convert I.sub.2 to 2I.sup.-, which antioxidant comprises an aqueous dissipating solution comprising from about 0.01% to about 5% by weight sorbic acid or a soluble salt thereof;
- from about 0.01% to about 5% by weight ethylenediaminetetraacetic acid or a soluble salt thereof;
- and about 0.1% to about 2% of an ammonium, alkali metal, or alkaline earth metal salt of a boron oxyacid.
Dependencies are inferred from the claim text.