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US 4,025,652 AGranted
Amidinoureas
AssigneeWilliam H. Rorer, Inc.
InventorsJulius Diamond, George H. Douglas
Life of this patent
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Abstract
A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-diarrheal agents.
Claims36
A method for the treatment of diarrhea in humans and mammals which comprises the administering thereto between 0.01 to 500 mg/kg per day of a compound of the formula:
- ##STR13## where:
- R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 may be the same or different and are:
- hydrogen,
- halo,
- loweralkyl,
- haloloweralkyl,
- nitro,
- loweralkoxy,
- hydroxy,
- arloweralkoxy,
- haloloweralkoxy or
- loweralkylsulfonyl;
- R and R.sub.n are hydrogen or loweralkyl;
- R' and R" are hydrogen,
- alkyl,
- cycloalkyl or
- aralkyl;
- and the non-toxic acid addition salts thereof.
15 more elements
Dependencies are inferred from the claim text.