Process for extruding green polyglycolic acid sutures and surgical elements
AssigneeAmerican Cyanamid Company
InventorsArthur Glick, Lester Daniel Chirgwin, Jr.
Life of this patent
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Abstract
Polyglycolic acid surgical elements, particularly sutures, are colored green to contrast with tissue, blood, and surroundings by extruding while melted the polyglycolic acid and concurrently in an optically homogeneous dispersion, from about 0.03% to 0.5% by weight of 1,4-bis(p-toluidino)-anthraquinone (D&C Green No. 6).
Claims9
A method of coloring polyglycolic acid surgical elements comprising incorporating 1,4-bis(p-toluidino)-anthraquinone into molten polyglycolic acid to form an optically homogeneous solution and forming solid pellets therefrom, and later melt spinning the green colored polyglycolic acid pellets into filaments in which the 1,4-bis(p-toluidino)-anthraquinone is uniformly dispersed in an optically homogeneously solid solution, said 1,4-bis(p-toluidino)-anthraquinone providing both color and lubricity to aid in extension in the melt spinning.
A method of coloring filamentary polyglycolic acid surgical elements comprising:
- intimately mixing dry 1,4-bis(p-toluidino)-anthraquinone and dry solid polyglycolic acid particles and melting to form an optically homogeneous solution, said 1,4-bis(p-toluidino)-anthraquinone and said polyglycolic acid melting and solidifying at about the same temperature,
- melt spinning the mixture through a spinnerette, solidifying the polyglycolic and 1,4-bis(p-toluidino)-anthraquinone concurrently to form a fiber, whereby the 1,4-bis(p-toluidino)-anthraquinone is uniformly dispersed in an optically homogeneous solid solution throughout the filamentary solid polyglycolic acid, and from which the 1,4-bis(p-toluidino)-anthraquinone is not leachable, and which on implantation and absorption by living mammalian tissue uniformly absorbs without tattooing,
- and subsequently stretching to orient,
- said 1,4-bis(p-toluidino)-anthraquinone providing both color and lubricity to aid in extrusion in the melt spinning.
Dependencies are inferred from the claim text.