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US 4,003,792 AGranted
Conjugates of acid polysaccharides and complex organic substances
AssigneeMiles Laboratories, Inc.
InventorsPatrick James Mill, Michael Alan Cresswell, Joseph George Feinberg
Life of this patent
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Abstract
This invention relates to chemical conjugates of acid polysaccharides and biochemically active complex organic molecules and particularly to such conjugates which are capable of forming soluble sodium salts and insoluble calcium salts.
Claims32
An immunologically active conjugate capable of forming soluble sodium salts and insoluble calcium salts comprising:
- an acid polysaccharide selected from the group consisting of pectin, pectic acid, alginic acid, celluronic acid, lichenin uronic acid, and carrageenan and comprising from about 93 to 98% of said conjugate, which polysaccharide is bonded covalently by a linkage selected from the group consisting of amide, ester, and a combination of amide and ester bonds to
- an immunologically active proteinaceous component selected from the group consisting of ovalbumin, lactalbumin, insulin, trypsin, chymotrypsin, ficin, Timothy pollen extract, cocksfoot pollen extract, ragweed pollen extract, birch pollen extract, horse dander extract, cat epithelium extract, haddock extract, dry rot extract, baker's yeast extract, tetanus toxoid, diptheria toxin, bee venom, and snake venom and comprising from about 2 to 7% of said conjugate.
Dependencies are inferred from the claim text.