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US 4,002,531 AGranted
Modifying enzymes with polyethylene glycol and product produced thereby
AssigneePierce Chemical Company
InventorGarfield P. Royer
Life of this patent
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Abstract
A process is disclosed for the preparation of the monoalkyl polyethyleneglycol derivatives of enzymes containing free amino groups. The process involves reductively alkylating the free amino groups of the enzyme with the aldehyde derivative of a monoalkyl polyethyleneglycol.
Claims1
A process for the preparation of the monoalkyl polyethyleneglycol derivative of an enzyme containing free amino groups comprising reductively alkylating the free amino groups of the enzyme with the aldehyde derivative of a monoalkyl polyethyleneglycol.
Dependencies are inferred from the claim text.