Blood gas control
AssigneeWarner-Lambert Company
InventorJames E. Turner
Life of this patent
Estimating the term…
Abstract
Disclosed are a stable, non-protein, buffered control material for monitoring the reliability of blood gas instruments in the acid, normal, and alkaline ranges.
Claims16
A liquid composition of matter for use as a blood gas control which comprises water, a dye, a buffering agent, a lower alkyl acid, a source of bicarbonate ion and an amount of dissolved oxygen, carbon dioxide and nitrogen gas.
The method for preparing a liquid blood gas control which comprises:
- Filtering a quantity of deionized water through a 0.22 .mu. filter membrane;
- Dissolving a quantity of a dye and triethanolamine in the filtered water;
- Adjusting the solution so obtained to a pH range of about 7.1 to 7.6;
- Dissolving a quantity of sodium bicarbonate in the pH adjusted solution;
- Placing the solution so obtained in a glass ampul;
- Flushing the ampul with a gas mixture comprising oxygen, carbon dioxide and nitrogen;
- Sealing the ampul to effect an air tight seal;
- and
- Sterilizing the ampul immediately after sealing in an autoclave.
A liquid composition or matter for use as a blood gas control which comprises water, a buffering agent, a lower alkyl acid, a source of bicarbonate ion and an amount of dissolved oxygen, carbon dioxide and nitrogen gas.
A composition of matter for use as a blood gas control which comprises water, triethanolamine acetic acid, sodium bicarbonate, and a gas mixture comprising oxygen in an amount of about 6.6 to about 21.9%, carbon dioxide in an amount of about 6.09 to about 6.75%, and nitrogen in an amount of about 71.35 to about 87.31%.
A composition of matter for use as a blood gas control which comprises water, F D, and C yellow dye, triethanolamine, sodium bicarbonate, acetic acid, an amount of dissolved gas comprising about 13% oxygen, about 6.4% carbon dioxide and about 80.6% nitrogen, and wherein the ratio of dye to triethanolamine to sodium bicarbonate is about 1 :
- 223.8 :
- 30.24 and wherein the pH of the composition is about 7.4.
A composition of matter for use as a blood gas control which comprises water, a dye selected from the group consisting of F D, and C yellow dye and F, and C Red No. 2, triethanolamine, acetic acid, sodium bicarbonate, and an amount of dissolved gas comprising 21.9% oxygen, 6.09% carbon dioxide and 72.01% nitrogen, and wherein the ratio of dye to triethanolamine to sodium bicarbonate is about 1 :
- 223.8 :
- 5.0, and wherein the pH of the composition is about 7.1.
A composition of matter for use as a blood gas control which comprises water, a dye selected from the group consisting of F D, and C yellow dye and CIF Blue No. 2, triethanolamine, acetic acid, sodium bicarbonate, an amount of dissolved gas comprising about 6.6% oxygen, about 6.75% carbon dioxide and about 86.65% nitrogen, and wherein the ratio of dye to triethanolamine to sodium bicarbonate is about 1 :
- 223.8 :
- 81.91 and wherein the pH of the composition is about 7.6.
A package for use in containing a liquid composition having a predetermined pH, oxygen concentration and carbon dioxide concentration which comprises:
- A sealed glass ampul wherein the seal is impermeable to air, and
- A liquid composition of matter comprising water, a dye, triethanolamine, acetic acid, sodium bicarbonate and a predetermined concentration of oxygen, carbon dioxide, and nitrogen, and wherein said liquid concentration is sterile.
Dependencies are inferred from the claim text.