Benzodiazepine derivatives
AssigneeKali-Chemie Aktiengesellschaft
InventorsWolfgang Milkowski, Renke Budden, Siegfried Funke, Rolf Huschens, Hans-Gunther Liepmann, Werner Stuhmer, Horst Zeugner
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AssigneeKali-Chemie Aktiengesellschaft
InventorsWolfgang Milkowski, Renke Budden, Siegfried Funke, Rolf Huschens, Hans-Gunther Liepmann, Werner Stuhmer, Horst Zeugner
Estimating the term…
A benzodiazepine derivative of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl which may be a straight chain, branched chain or cyclic group and may also be substituted, R.sub.2 is halogen, free hydroxyl, esterified hydroxyl, etherified hydroxyl, nitrile, carboxyl or a derivative thereof or is thioalkyl, thioaryl or the group ##STR2## R.sub.3 and R.sub.4 in this group being the same or different and being hydrogen, acyl, aryl, alkyl, aralkyl, aryloxyalkyl which latter five groups may also be substituted, or wherein R.sub.3 and R.sub.4 are saturated or unsaturated, straight chain or branched alkyl and in which groups the several alkyl may be interconnected directly or through a hetero atom, which if the hetero atom is nitrogen may also be substituted, And in which formula I, A and B are phenyl or phenyl substituted by nitro, trifluoromethyl, halogen, methylthio alkyl or alkoxy; Or a pharmaceutically acceptable acid addition salt of said benzodiazepine derivatives of formula I.
A benzodiazepine derivative having the formula ##STR25## in which R.sup.1 is hydrogen, methyl, ethyl, benzyl, or 2-chloroethyl,
Dependencies are inferred from the claim text.