Back to results
US 3,994,912 AGranted
1-Oxides of Schiff bases of 6-aminopenicillanic acid
AssigneeE. R. Squibb & Sons, Inc.
InventorsDouglas Barry Davis, Ekkehard Bohme, Joseph Edward Dolfini
Life of this patent
Estimating the term…
Abstract
Compounds containing a cephem nucleus are prepared by heating a 1-oxide of a Schiff base of 6-aminopenicillanic acid. These cephem compounds are useful as intermediates in the preparation of physiologically active cephalosporins.
Claims7
A compound of the formula ##EQU1## wherein R is a monocyclic or dicyclic carbocyclic aromatic group;
- alkyl;
- halo, hydroxy, nitro or alkoxy substituted alkyl;
- monocyclic carbocyclic aryl(lower alkyl);
- monocyclic carbocyclic aryl(lower alkenyl);
- furyl;
- thiophenyl;
- or pyridyl and R" is hydrogen;
- an alkali metal, alkaline earth metal, ammonium or organic ammonium radical;
- or a conventional esterifying group.
6 more elements
Dependencies are inferred from the claim text.