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US 3,988,340 AGranted
6-Alkoxymethyl-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones and 7-alkoxymethyl-6-[H]-1,2,3,4-tetrahydropyrimido[2,1-b]quinazolin-2-ones
AssigneeBristol-Myers Company
InventorsRichard Anthony Partyka, Warren Neil Beverung, Jr.
Life of this patent
Estimating the term…
Abstract
Optionally substituted 6-alkoxymethyl-1,2,3,5-tetrahydroimidazo[2,1-b]-quinazolin-2-ones and 7-alkoxymethyl-6-[H]-1,2,3,4-tetrahydropyrimido[2,1-b]-quinazolin-2-ones or the pharmaceutically acceptable salts thereof are compounds useful as blood platelet anti-aggregative and/or antihypertensive and/or bronchodilator agents in mammals, including humans.
Claims14
A compound having the formula ##SPC44##
- in which R.sup.1 is H, phenyl or (lower)alkyl, R is (lower)alkyl, R.sup.2 is hydrogen, chloro, bromo, fluoro, CF.sub.3, hydroxy, (lower)alkyl of 1 to 3 carbon atoms or (lower)alkoxy of 1 to 3 carbon atoms and n is an integer of 1 or 2;
- or a pharmaceutically acceptable acid addition salt thereof.
The compound having the formula ##SPC50##
- or a pharmaceutically acceptable acid addition salt thereof.
The compound having the formula ##SPC51##
- or a pharmaceutically acceptable acid addition salt thereof.
The compound having the formula ##SPC52##
- or a pharmaceutically acceptable acid addition salt thereof.
Dependencies are inferred from the claim text.