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US 3,975,533 AGranted
Therapeutic agents
AssigneeShell Oil Company
InventorsJiro K. Kodama, George R. Haynes, James R. Albert
Life of this patent
Estimating the term…
Abstract
O-HALOBENZYLIDENEAMINOGUANIDINES ARE EMPLOYED AS CENTRAL NERVOUS SYSTEM DEPRESSANTS, AS CARDIOVASCULAR DEPRESSANTS, AND/OR AS ANTIDEPRESSANTS FOR OVERCOMING PSYCHIC DEPRESSION.
Claims2
A method for combatting psychic depression in mammals which comprises administering to a psychically depressed mammal in need of said treatment an effective dosage for combatting the psychic depression of the compound of the formula ##SPC3##
- wherein X is halogen or trifluoromethyl, Y and Z may be the same or different and are hydrogen, halogen, trifluoromethyl or alkyl of 1 to 4 carbon atoms, R, R',R" and R.degree. each hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 4 carbon atoms or alkynyl of 2 to 4 carbon atoms with the proviso that R" and R.degree. may together form an alklene or alkenylene bridge of 2 to 4 carbon atoms, with the further proviso that one of Y and R must be hydrogen, or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.