[1-Hydroximino-2,2-disubstituted-5-indanyloxy-(or thio)]alkanoic acids

A compound of the formula:

• ##SPC24##
• wherein
• A is oxygen or sulphur;
• R is lower alkyl, cycloalkyl having from 3 to 6 carbon atoms, phenyl, or halo-, hydroxy-, lower alkoxy-, nitro or lower alkyl-substituted phenyl;
• R.sup.1 is lower alkyl, lower alkenyl having from 3 to 5 carbon atoms, lower alkynyl, containing from 3 to 5 carbon atoms, phenyl lower alkyl, phenyl lower alkenyl, hydroxy lower alkyl, lower alkoxy lower alkyl, oxo lower alkyl, hydroxy cycloalkyl having from 4 to 6 carbon atoms and cycloalkyl lower alkyl having 4 to 7 carbon atoms;
• R and R.sup.1 may be joined together with the carbon atom to which they are attached to form a cycloalkyl radical containing from 3 to 7 nuclear carbon atoms, or a hydroxy, or lower alkyl substituted cycloalkyl radical having from 3 to 7 nuclear carbon atoms;
• R.sup.2 is hydrogen, lower alkyl, phenyl, or lower alkyl substituted phenyl;
• R.sup.n is hydrogen, or methyl;
• R.sup.1 and R.sup.2 may be joined together to form a hydrocarbylene ring having up to 5 carbon atoms;
• X.sup.1 is hydrogen, methyl or halo;
• and
• X.sup.2 is methyl or halo;
• or
• X.sup.1 and X.sup.2 may be joined to form a hydrocarbylene chain containing 3 to 4 carbon atoms;
• and
• Y is alkylene or haloalkylene containing from 1 to about 4 carbon atoms, and the non-toxic pharmacologically acceptable salt derivatives thereof.