Back to results
US 3,966,766 AGranted
Monocyclic macrocyclic compounds and complexes thereof
AssigneeSchering Corporation
InventorJean-Marie Lehn
Life of this patent
Estimating the term…
Abstract
Novel monocyclic macrocyclic compounds having nitrogen bridgehead atoms and having in the hydrocarbon bridging chains at least two additional hetero atoms selected from the group consisting of sulfur, oxygen, and nitrogen, when admixed with a compatible cation-donor compound form stable cation-containing macrocyclic complexes which, in turn, can be conveniently dissociated by addition of acid or a quaternizing agent. The novel macrocyclics are valuable for use in the same way and for the same purposes as chelating agents.
Claims13
A macrocyclic compound selected from the group consisting of a compound of the following formula I:
- ##SPC33##
- wherein R.sub.1 and R.sub.2 and members selected from the group consisting of hydrogen and a hydrocarbon radical having up to 12 carbon atoms;
- wherein each A is a hydrocarbon radical having from 2 to 8 carbon atoms;
- each D is a member selected from the group consisting of oxygen, sulfur, a hydrocarbon radical having up to 8 carbon atoms, and =N--R (R being a member selected from the group consisting of hydrogen, a hydrocarbon radical having up to 12 carbon atoms, an aryl hydrocarbonsulfonyl radical having up to 12 carbon atoms, a lower alkoxycarbonyl radical, a lower alkoxycarbonylmethylene radical and a carboxymethylene radical);
- at least two of said D members being hetero-substituents selected from the group consisting of oxygen, sulfur and =N--R;
- one of said two hetero-substituents being selected from the group consisting of oxygen and sulfur, the other of said two heterosubstituents being selected from the group consisting of oxygen and =N--R;
- m and n are integers from 0 to 5;
- and the ammonium quaternary salts and acid addition salts thereof.
5 more elements
Dependencies are inferred from the claim text.