Substituted morpholine guanidines for the treatment of arrhythmic conditions
AssigneeThe Upjohn Company
InventorDonald W. DuCharme
Life of this patent
Estimating the term…
Abstract
The pharmaceutical compositions and methods of using these compositions for anti-arrhythmic and diuretic uses are disclosed for the compounds below: ##EQU1##
Claims11
A method for the treatment of arrhythmic conditions in mammals which comprises administering to said mammal an anti-arrhythmic effective amount of a compound of the formula ##EQU18## wherein R.sub.1 and R.sub.2 are the same or different and are selected from the group consisting of alkyl of from four to seven carbon atoms, inclusive cycloalkyl of from five to seven carbon atoms, inclusive, phenyl, phenalkyl with alkyl of from one to three carbon atoms, inclusive, and mono-substituted phenyl and phenyl moiety of the phenalkyl wherein the substituent is selected from the group consisting of alkyl of one to three carbon atoms, inclusive, alkoxy of from one to three carbon atoms, inclusive, halogen, and trifluoromethyl;
- and pharmaceutically acceptable acid addition salts thereof in association with a pharmaceutical carrier.
Dependencies are inferred from the claim text.